Lista completa de Publicações

@article{Souza2025,

title = {Brazilian profile of Radium-223 in metastatic prostate cancer: a multicentric, retrospective study},

author = {Stephan Souza and Felipe Ribeiro and Ana Brito and Thaís Minekawa and Flávia Lopes and Sumara Matedi and Renata Fockink and Dalton Anjos and Gustavo Gomes and Laura Silva and Mariana Camacho and Allan Santos and Whemberton Araújo and Ana Teixeira and Raul Martins and Adelina Sanches and Nilton Hanaoka and Rafael Tavares and Felipe Villela-Pedras and Felipe Mourato and Caroline Torricelli and Thiago Alves and Marcelo Tavares and Mariana Lima and André Moraes and André Sasse and Paulo Almeida and Elba Etchebehere},

doi = {10.1186/s41824-025-00245-9},

issn = {3005-074X},

year  = {2025},

date = {2025-12-00},

urldate = {2025-12-00},

journal = {EJNMMI Rep.},

volume = {9},

number = {1},

publisher = {Springer Science and Business Media LLC},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Carrilho2025b,

title = {Prognostic impact of low muscularity in metastatic and recurrent head and neck cancer: Insights from C3-based assessments},

author = {Larissa Ariel Oliveira Carrilho and Livia Dias Guerra and Rafaella Caroline de Lellis Moreira and Fabiana Lascala Juliani and Fernanda Silva Santos and Daniela Morais de Holanda Padilha and Fabíola Furtuoso Zaperlão and Sandra Regina Branbilla and Vivian Naomi Horita and Davi Magalhães Leite Novaes and Lígia Moraes Antunes-Correa and Carmem Silvia Passos Lima and Maria Carolina Santos Mendes and José Barreto Campello Carvalheira},

doi = {10.1016/j.clnesp.2025.06.029},

issn = {2405-4577},

year  = {2025},

date = {2025-08-00},

urldate = {2025-08-00},

journal = {Clinical Nutrition ESPEN},

volume = {68},

pages = {767--773},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Carrilho2025,

title = {Adipose tissue characteristics as a new prognosis marker of patients with locally advanced head and neck cancer},

author = {Larissa Ariel Oliveira Carrilho and Fabiana Lascala Juliani and Rafaella Caroline de Lellis Moreira and Livia Dias Guerra and Fernanda Silva Santos and Daniela Morais de Holanda Padilha and Sandra Regina Branbilla and Vivian Naomi Horita and Davi Magalhães Leite Novaes and Lígia Macedo Antunes-Correa and Carmem Silvia Passos Lima and Maria Carolina Santos Mendes and José Barreto Campello Carvalheira},

doi = {10.3389/fnut.2025.1472634},

issn = {2296-861X},

year  = {2025},

date = {2025-03-14},

urldate = {2025-03-14},

journal = {Front. Nutr.},

volume = {12},

publisher = {Frontiers Media SA},

abstract = {<jats:sec><jats:title>Background</jats:title><jats:p>Patients with head and neck cancer (HNC) are at increased risk of malnutrition due to the presence of tumor and treatments. Body composition is a prognostic factor in these patients. However, the relationship between adipose tissue characteristics and survival in HNC is still unclear.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>To evaluate the associations of adiposity, the radiodensity of adipose tissue and muscularity with the prognosis of patients with locally advanced HNC undergoing to chemoradiotherapy.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This retrospective study included 132 patients diagnosed with locally advanced HNC. Body composition assessment was performed using computed tomography (CT) images at the level of the third cervical vertebra (C3). The total adipose tissue radiodensity (TATR), the total adipose tissue index (TATI) and skeletal muscle index (SMI) were evaluated. The primary outcome was overall survival (OS).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Patients in the highest TATI tertile had a lower risk of mortality when compared to those in the lowest tertile, HR: 0.56, 95% confidence Interval (CI): 0.32–0.96; <jats:italic>p</jats:italic> = 0.039. The highest TATR tertile was not associated with death. Patients with greater adiposity had a higher median survival compared to patients with medium and lower TATI (<jats:italic>p</jats:italic> = 0.0193). Individuals with lower TATI had lower energy intake than patients with higher TATI (<jats:italic>p</jats:italic> = 0.03). Additionally, patients with low muscularity had worse OS in the multivariable analysis (HR: 1.77, 95% CI: 1.01–3.07; <jats:italic>p</jats:italic> = 0.044).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>In patients with locally advanced HNC, our findings underscore the significance of elevated adiposity, beyond maintained muscularity, as independent protective factors for overall survival. Our study highlights the critical importance of assessing body composition and initiating early nutritional interventions to improve the prognosis of these patients.</jats:p></jats:sec>},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{deMenezesPereira2025,

title = {Antibacterial profile and antiproliferative activities over human tumor cells of new silver(I) complexes containing two distinct trifluoromethyl uracil isomers},

author = {Gabriele de Menezes Pereira and Julia H. Bormio Nunes and Vinicius Souza Macedo and Douglas Henrique Pereira and Kaio Eduardo Buglio and Daniele D. Affonso and Ana Lucia T.G. Ruiz and João Ernesto de Carvalho and Silmara Cristina L. Frajácomo and Wilton R. Lustri and Carmen Silvia Passos Lima and Fernando R.G. Bergamini and Alexandre Cuin and Norberto Masciocchi and Pedro Paulo Corbi},

doi = {10.1016/j.jinorgbio.2024.112752},

issn = {0162-0134},

year  = {2025},

date = {2025-01-00},

urldate = {2025-01-00},

journal = {Journal of Inorganic Biochemistry},

volume = {262},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Genaro2025,

title = {Therapeutic drug monitoring and immunogenetic factors associated with the use of adalimumab in Crohn’s disease patients},

author = {Livia Moreira Genaro and Juliana Carron and Marina Moreira de Castro and Ana Paula Menezes de Freitas Franceschini and Gustavo Jacob Lourenço and Cristiane Kibune Nagasako Vieira da Cruz and Glaucia Fernanda Soares Rupert Reis and Livia Bitencourt Pascoal and Juliana Delgado Campos Mello and Isabela Machado Pereira and Millene Leal Nascimento and Priscilla De Sene Portel Oliveira and Ligiana Pires Corona and Maria de Lourdes Setsuko Ayrizono and Carmen Silvia Passos Lima and Raquel Franco Leal},

doi = {10.1177/03946320251319379},

issn = {2058-7384},

year  = {2025},

date = {2025-01-00},

urldate = {2025-01-00},

journal = {Int J Immunopathol Pharmacol},

volume = {39},

publisher = {SAGE Publications},

abstract = {<jats:p> Crohn’s disease (CD) involves immune system interactions with intestinal tissue, driven by pro-inflammatory cytokines like Tumor Necrosis Factor (TNF-α). Adalimumab, targeting TNF-α, regulates associated inflammatory responses. Despite being humanized, it may induce immunogenic processes, affecting treatment effectiveness. Thus, monitoring serum adalimumab and anti-drug antibody (ADA) levels can optimize therapy. Understanding genetic factors influencing adalimumab response can enhance personalized treatment and improve patient quality of life. We aimed to quantify adalimumab serum levels, assess test interchangeability, detect ADA, examine immune complex formation, and investigate genetic phenotypes related to immunogenicity in CD patients. Seventy CD patients in the maintenance phase with adalimumab were classified into active (CDA) and remission (CDR) groups. Adalimumab concentration was determined via enzyme-linked immunosorbent assay (ELISA—Promonitor) and lateral flow assay (Quantum Blue), with assay interchangeability assessed statistically. ADA and immune complex formation were quantified using ELISA assays. DNA was genotyped for the genes ATG16L1, CD96, and CD155. No significant differences in adalimumab serum concentrations were observed between groups, regardless of the assay. However, a statistical difference between the tests indicated measurement disparity ( P = 0.003), with moderate agreement (Lin’s correlation of 0.247). ADA was detected in 4 of 27 of the patients with infratherapeutic levels, 3 in the CDA group and 1 in the CDR group. Analysis of immune complexes revealed significantly higher concentrations in the CDA group ( P = 0.0125). The genotypic evaluation revealed significant associations for the CD96 CC (wild-type) genotype with higher CRP levels, colonic involvement, and infratherapeutic levels of adalimumab. ATG16L1 CC genotype was associated with higher CDEIS and fecal calprotectin values, while the variant (TT) genotype had lower platelet counts. The effectiveness of treatment with adalimumab was not directly related to higher medication levels in this cohort. The disparity between tests indicates the need to use only one test in patient follow-up to ensure accuracy in therapeutic monitoring. Genotypic differences highlight the correlation between the wild genotype for CD96 and ATG16L1 with unfavorable laboratory and endoscopic response to adalimumab. Finally, the more significant levels of immune complexes in the CDA group indicate an association with a worse response to adalimumab. </jats:p>},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Liveraro2025,

title = {Improving resectable gastric cancer prognosis prediction: A machine learning analysis combining clinical features and body composition radiomics},

author = {Gianni S.S. Liveraro and Maria E.S. Takahashi and Fabiana Lascala and Luiz R. Lopes and Nelson A. Andreollo and Maria C.S. Mendes and Jun Takahashi and José B.C. Carvalheira},

doi = {10.1016/j.imu.2024.101608},

issn = {2352-9148},

year  = {2025},

date = {2025-00-00},

urldate = {2025-00-00},

journal = {Informatics in Medicine Unlocked},

volume = {52},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Padilha2024,

title = {Subcutaneous adipose tissue radiodensity: An emerging risk factor for severe COVID-19},

author = {Daniela M.H. Padilha and Maria C.S. Mendes and Maria E.S. Takahashi and Fabiana Lascala and Marina N. Silveira and Lara Pozzuto and Larissa A.O. Carrilho and Lívia D. Guerra and Rafaella C.L. Moreira and Sandra R. Branbilla and Celso Darío Ramos and José B.C. Carvalheira},

doi = {10.1016/j.nut.2024.112561},

issn = {0899-9007},

year  = {2024},

date = {2024-12-00},

urldate = {2024-12-00},

journal = {Nutrition},

volume = {128},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Carron2024b,

title = {The impact of ERP29 on the progression of pharyngeal squamous cell carcinoma},

author = {Juliana Carron and Lilian de Oliveira Coser and Carmen Silvia Passos Lima and Gustavo Jacob Lourenço},

doi = {10.1038/s41598-024-76210-6},

issn = {2045-2322},

year  = {2024},

date = {2024-12-00},

urldate = {2024-12-00},

journal = {Sci Rep},

volume = {14},

number = {1},

publisher = {Springer Science and Business Media LLC},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Nogueira-Lima2024,

title = {18F-Fluoride PET/CT—Updates},

author = {Ellen Nogueira-Lima and Thiago Alves and Elba Etchebehere},

doi = {10.1053/j.semnuclmed.2024.09.005},

issn = {0001-2998},

year  = {2024},

date = {2024-11-00},

urldate = {2024-11-00},

journal = {Seminars in Nuclear Medicine},

volume = {54},

number = {6},

pages = {951--965},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Silva2024c,

title = {Assessing the role of prognostic nutritional index in predicting outcomes for rectal cancer surgery},

author = {Amanda Cristina Ribeiro Silva and Lígia de Moraes Antunes-Correa and Fabiana Lascala Juliani and Larissa Ariel Oliveira Carrilho and Felipe Osório Costa and Carlos Augusto Real Martinez and Maria Carolina Santos Mendes and José Barreto Campello Carvalheira},

doi = {10.1016/j.clnesp.2024.07.1058},

issn = {2405-4577},

year  = {2024},

date = {2024-10-00},

urldate = {2024-10-00},

journal = {Clinical Nutrition ESPEN},

volume = {63},

pages = {644--650},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Almeida2024,

title = {Radioligand Therapy in Lymphoma},

author = {Ludmila Santiago Almeida and Roberto C. Delgado Bolton and Victor Cabral Heringer and Samuel de Souza Medina and Elba Etchebehere},

doi = {10.1016/j.cpet.2024.05.003},

issn = {1556-8598},

year  = {2024},

date = {2024-07-00},

urldate = {2024-07-00},

journal = {PET Clinics},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Heringer2024,

title = {177LU-PSMA IN METASTATIC CASTRATION RESISTANT PROSTATE CANCER: PRELIMINARY ANALYSIS OF A BRAZILIAN MULTICENTRIC STUDY},

author = {Victor Cabral Costa Ribeiro Heringer and Felipe P.G. Ribeiro and Diogo Bastos and Camila Mosci and Dalton A. Anjos and Paulo Almeida Filho and Gustavo Gomes and Filipe Villela-Pedras and Fabio Ribeiro and Julio Correia and José F. Marin and Carlos Buchpiguel and Elba C.S.C. Etchebehere},

doi = {10.1016/j.htct.2024.04.071},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{doNascimento2024,

title = {18F-FLUORIDE PET/CT vs 18F-PSMA-1007 TO DETECT BONE METASTASES IN PROSTATE CANCER – A HEAD-TO-HEAD PROSPECTIVE COMPARISON},

author = {Beatriz Birelli do Nascimento and Allan Santos and Natalia Tobar and Fabiana Mori and Mariana Camacho and Mariana Lima and Edna Brunetto and Sergio Brunetto and Anelise Ruzzarin and Juliana Ciampi and Marina Silveira and Gardenia Oliveira Barbosa and Wagner Matheus and Ubirajara Ferreira and Elba Etchebehere},

doi = {10.1016/j.htct.2024.04.088},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

pages = {S24--S25},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Heringer2024d,

title = {ARTIFICIAL INTELLIGENCE TO EVALUATE METABOLIC TUMOR BURDEN IN PRIMARY STAGING OF RECTAL CANCER WITH 18F-FDG PET/CT},

author = {Victor Cabral Costa Ribeiro Heringer and Maria Carolina S. Mendes and Barbara Juarez Amorim and Allan Oliveira Santos and Marina N. Silveira and Cleide Silva and Juliano S. Fonseca and Mariana C.L. Lima and Lorena P. Cunha and Carlos Augusto R. Martinez and Claudio Coy and Jose Barreto C. Carvalheira and Elba Cristina Sá de Camargo Etchebehere},

doi = {10.1016/j.htct.2024.04.054},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

pages = {S3--S4},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Silveira2024,

title = {COMPARISON OF 18F-FDG AND 18F-PSMA PET/CT IN PATIENTS WITH NON-SMALL CELL LUNG CANCER},

author = {Najua Abou Arabi Silveira and Maurício Wesley Perroud Júnior and Hugo Nakano Ide and Kaique Moraes do Amaral and Simone Kuba and Natália Tobar and Thiago Ferreira de Souza and Carmen Silva Passos Lima and José Barreto Campello Carvalheira and Barbara Juarez Amorim and Elba Cristina Sá de Camargo Etchebehere and Mariana da Cunha Lopes de Lima and Allan de Oliveira Santos and Ludimila Santiago Almeida and Maria Emília Seren Takahashi and Eliana Cristina Martins Miranda and Carmino Antonio de Souza and Sérgio Querino Brunetto and Celso Dario Ramos},

doi = {10.1016/j.htct.2024.04.079},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Sousa2024,

title = {COMPARISON OF 18 F-FDG AND 18 F-PSMA-1007 PET/CT IN ADVANCED LOCOREGIONAL SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: PRELIMINARY RESULTS},

author = {Hadila Da Silva Veras Sousa and Kaique Moraes do Amaral and Najua Abou Arab and Simone Kuba and Lígia Traldi Macedo and Bárbara Juarez Amorim and Celso Dario Ramos and Carmen Silvia Passos Lima},

doi = {10.1016/j.htct.2024.04.084},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

pages = {S22--S23},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Tineo2024,

title = {COMPARISON BETWEEN PET/CT WITH 18F-PSMA-1007 AND WITH 18F-FDG IN MUSCLE-INVASIVE BLADDER UROTHELIAL CARCINOMA},

author = {Ricardo Norberto Tineo and Natalia Dalsenter Avilez and Juliano Tomé Rodrigues and Felipe Piccarone G Ribeiro and Helena Paes de Alm de Saito and Frederico Leal and Barbara Juazer Amorim and Jose Barrreto C. Carvalheira and Leonardo Oliveira Reis and Celso Dario Ramos},

doi = {10.1016/j.htct.2024.04.086},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

pages = {S23--S24},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Silva2024,

title = {COMPARISON OF PET/CT IMAGES WITH 18F-FDG AND 18F-PSMA-1007 IN MUSCULOSKELETAL TUMORS TO EVALUATE THE POTENTIAL OF THERANOSTICS APPROACH},

author = {Mayara Branco E. Silva and Natalia Tobar and Allan de Oliveira Santos and Gardenia De Oliveira Barbosa and Carlos Eduardo Hideo Hanasilo and Mariana Da Cunha Lopes de Lima and Mauricio Etchebehere and Elba Cristina Sa de Camargo Etchebehere},

doi = {10.1016/j.htct.2024.04.089},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

pages = {S25--S26},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Mendanha2024,

title = {COMPARISON OF PET/CT IMAGES WITH 18F-FDG AND 18F-PSMA-1007 IN METASTATIC ACRAL MELANOMA: A CASE REPORT},

author = {Diego Machado Mendanha and Natalia Tobar and Ligia Traldi Macedo and Allan Oliveira Santos and Mariana Cunha Lopes de Lima and Elba Cristina Sá de Camargo Etchebehere and Carmen Silvia Passos Lima},

doi = {10.1016/j.htct.2024.04.102},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}

@article{Sousa2024b,

title = {COMPARISON OF PET/CT IMAGES WITH 18 F-FDG AND 18 F-PSMA-1007 IN RELAPSED ADENOID CYSTIC CARCINOMA},

author = {Hadila Da Silva Veras Sousa and Natália Tobar and Lígia Traldi Macedo and Simone Kuba and Allan de Oliveira Santos and Bárbara Juarez Amorim and Carmen Silvia Passos Lima and Elba Cristina Sá de Camargo Etchebehere},

doi = {10.1016/j.htct.2024.04.082},

issn = {2531-1379},

year  = {2024},

date = {2024-04-00},

urldate = {2024-04-00},

journal = {Hematology, Transfusion and Cell Therapy},

volume = {46},

publisher = {Elsevier BV},

keywords = {Área Clínica},

pubstate = {published},

tppubtype = {article}

}