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CancerThera - Equipe - Jose Vassallo

Pesquisador Associado

Professor Titular de Patologia. Departamento de Anatomia Patológica da Faculdade de Ciências Médicas da Universidade Estadual de Campinas – Unicamp

José Vassallo

Linhas de Pesquisa
  • Marcadores tumorais detectados por imunoistoquímica
  • Caracterização de neoplasias hematológicas
  • Oncogênese viral: papilomavírus humano; vírus de Epstein-Barr; Herpesvirus humano tipo 8
  • Microambiente tumoral: matriz extracelular e infiltrado inflamatório relacionado ao tumor

Oncopatologia

Hematopatologia

Patologia molecular

Produção Científica
  1. Assis-Mendonça GR, Campos LG, Delamain MT, de Brito ABC, Fanelli MF, Soares FA, de Souza CA, Vassallo J, Lima CSP. Association of single nucleotide variants in VEGFA and KDR with the risk and angiogenic features of diffuse large B-cell lymphoma. Leuk Lymphoma. 2023 Aug 30:1-13. doi:10.1080/10428194.2023.2248330. Epub ahead of print. PMID: 37647140.
  2. Hoffmann LG, Sarian LO, Vassallo J, de Paiva Silva GR, Ramalho SOB, Ferracini AC, da Silva Araujo K, Jales RM, Figueira DE, Derchain S. Evaluation of PD-L1 and tumor infiltrating lymphocytes in paired pretreatment biopsies and post neoadjuvant chemotherapy surgical specimens of breast carcinoma. Sci Rep. 2021 Nov 18;11(1):22478. doi: 10.1038/s41598-021-00944-w. PMID: 34795307; PMCID: PMC8602240.
  3. Cunha LL, Domingues GAB, Morari EC, Soares FA, Vassallo J, Ward LS. The immune landscape of the microenvironment of thyroid cancer is closely related to differentiation status. Cancer Cell Int. 2021 Jul 20;21(1):387. doi: 10.1186/s12935-021-02084-7. PMID: 34284788; PMCID: PMC8293508.
  4. Brito ABC, Delamain MT, Fanelli MF, Soares FA, de Souza CA, Vassallo J, Lima CSP. Angiogenesis' related genetic variants alter clinical features and prognosis of diffuse large B-cell lymphoma patients. Tumour Biol. 2021;43(1):129-140. doi: 10.3233/TUB-211510. PMID: 34219681.
  5. Assis-Mendonça GR, Fattori A, Rocha RM, Lourenço GJ, Delamain MT, Nonogaki S, de Lima VCC, Colleoni GWB, de Souza CA, Soares FA, Lima CSP, Vassallo J. Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma. BMC Cancer. 2021 Mar 1;21(1):209. doi: 10.1186/s12885-021-07891-9. PMID: 33648463; PMCID: PMC7919095.
  6. Assis-Mendonça GR, Lourenço GJ, Delamain MT, de Lima VCC, Colleoni GWB, de Souza CA, Soares FA, Lima CSP, Vassallo J. Single-nucleotide variants in TGFB1, TGFBR2, IL17A, and IL17F immune response genes contribute to follicular lymphoma susceptibility and aggressiveness. Blood Cancer J. 2020 Oct 6;10(10):97. doi: 10.1038/s41408-020-00365-4. PMID: 33024088; PMCID: PMC7538580.
  7. Assis-Mendonça GR, Fattori A, Rocha RM, Lourenço GJ, Delamain MT, Nonogaki S, de Lima VCC, Colleoni GWB, de Souza CA, Soares FA, Lima CSP, Vassallo J. An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course. Oncotarget. 2020 Aug 18;11(33):3153-3173. doi: 10.18632/oncotarget.27698. PMID: 32913559; PMCID: PMC7443366.
  8. Melo-Hanchuk TD, Martins MB, Cunha LL, Soares FA, Ward LS, Vassallo J, Kobarg J. Expression of the NEK family in normal and cancer tissue: an immunohistochemical study. BMC Cancer. 2020 Jan 6;20(1):23. doi: 10.1186/s12885-019-6408-4. PMID: 31906878; PMCID: PMC6945616.
  9. Natal RA, Paiva GR, Pelegati VB, Marenco L, Alvarenga CA, Vargas RF, Derchain SF, Sarian LO, Franchet C, Cesar CL, Schmitt FC, Weigelt B, Vassallo J. Exploring Collagen Parameters in Pure Special Types of Invasive Breast Cancer. Sci Rep. 2019 May 22;9(1):7715. doi: 10.1038/s41598-019-44156-9. PMID: 31118443; PMCID: PMC6531485.
  10. Natal RA, Vassallo J, Paiva GR, Pelegati VB, Barbosa GO, Mendonça GR, Bondarik C, Derchain SF, Carvalho HF, Lima CS, Cesar CL, Sarian LO. Collagen analysis by second-harmonic generation microscopy predicts outcome of luminal breast cancer. Tumour Biol. 2018 Apr;40(4):1010428318770953. doi: 10.1177/1010428318770953. PMID: 29663855.
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